autophagic vacuoles
The autophagic vacuoles are membrane-bound vacuoles within the cell that contain fragments of cell components (e.g., mitochondria, endoplasmic reticulum) that are destined for destruction and into which the lysosomes discharge their hydrolytic contents (autophagy). The cellular components are then digested.
Some of the cell debris within the autophagic vacuole may resist digestion and persist as membrane-bound residual bodies that may remain in the cytoplasm. An example of such residual bodies is the lipofuscin granules (lipofuscin deposits). When present in sufficient amounts, they impart a brown discoloration to the tissue (brown atrophy).