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PI1

MIM.107400 14q32.1

Alpha-1-antitrypsin is a protease inhibitor, deficiency of which is associated with emphysema and liver disease. The protein is encoded by a gene (PI1) located on the distal long arm of chromosome 14.

Pathology

- alpha-1-antitrypsin deficiency (PI1 deficiency)

See also

- serpins

  • serpinopathies

- conformational diseases