WASPs
WASP (MIM.301000), WASP-like (WASL) (MIM.605056), and WASF1 are among the downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton.
References
Stradal TE, Rottner K, Disanza A, Confalonieri S, Innocenti M, Scita G. Regulation of actin dynamics by WASP and WAVE family proteins. Trends Cell Biol. 2004 Jun;14(6):303-11. PMID: #15183187#
Snapper SB, Rosen FS. A family of WASPs. N Engl J Med. 2003 Jan 23;348(4):350-1. PMID: #12540651#
Snapper SB, Rosen FS: The Wiskott-Aldrich syndrome protein (WASP): roles in signaling and cytoskeletal organization. Annu Rev Immunol 17:905, 1999.