renal solitary fibrous tumor
Solitary fibrous tumor (SFT) is a neoplasm that can occur in the urogenital tract, and is also reported occurring in the spermatic cord, seminal vesicles, urinary bladder, prostate, and kidney.
Synopsis
proliferation of bland-looking vimentin+, CD34+, bcl2+ and CD99+ spindle cells
haphazard growth pattern
storiform growth pattern, pushing borders
low mitotic rate (2 mitoses x 10 HPF)
Differential diagnosis
other primary monomorphous benign and malignant spindle cell tumors of the kidney
- fibroma
- benign fibrous histiocytoma
- hemangiopericytoma
- inflammatory myofibroblastic tumor
- leiomyoma
- angiomyolipoma with predominant spindle cell smooth muscle component
- benign peripheral nerve sheath tumors
- renal mixed epithelial/stromal tumors
- adult type mesoblastic nephroma
- fibrous type monophasic synovial sarcoma
- malignant peripheral nerve sheath tumors
- adult-type fibrosarcoma
- low-grade fibromyxoid sarcoma
References
Magro G, Cavallaro V, Torrisi A, Lopes M, Dell’Albani M, Lanzafame S. Intrarenal solitary fibrous tumor of the kidney report of a case with emphasis on the differential diagnosis in the wide spectrum of monomorphous spindle cell tumors of the kidney. Pathol Res Pract. 2002;198(1):37-43. PMID: #11866209#