indolent NK-cell lymphoproliferative disorder

Indolent NK-cell lymphoproliferative disorder, also known as chronic natural killer (NK) cell large granular lymphocytosis (leukemia), is a very rare entity in the World Health Organization (WHO) Classification of Tumors of Hematopoietic & Lymphoid Tissues.

Complication

 aggressive extranodal NK/T-cell lymphoma (16224224)

References

 Huang Q, Chang KL, Gaal KK, Weiss LM. An Aggressive Extranodal NK-Cell Lymphoma Arising From Indolent NK-Cell Lymphoproliferative Disorder. Am J Surg Pathol. 2005 Nov;29(11):1540-3. PMID: 16224224