oncocytic tumors
Hamperl introduced the term "oncocyte" in 1931 referring to a cell with abundant, granular, eosinophilic cytoplasm.
Electron microscopic studies revealed that this granularity was due to mitochondria accumulation in the oncocyte cytoplasm.
Neoplasms composed predominantly or exclusively of this kind of cells are called "oncocytic".
Such tumours have been described in the overwhelming majority of organs: kidney, thyroid and pituitary gland, salivary, adrenal, parathyroid and lacrimal glands, paraganglia, respiratory tract, paranasal sinuses and pleura, liver, pancreatobiliary system, stomach, colon and rectum, central nervous system, female and male genital tracts, skin and soft tissues.