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CFH

MIM.134370 1q32

Pathology

- germline mutations in

  • autosomal dominant hemolytic-uremic syndrome (MIM.235400)
  • autosomal recessive hemolytic-uremic syndrome (MIM.235400)
  • atypical nondiarrhea-associated HUS (MIM.235400)
  • hypocomplementemic chronic nephropathy (hypocomplementemic hypertensive renal disease)
  • combined factor H and FHL1 deficiency
  • age-related macular degeneration (MIM.603075)