CPAM type 1
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CCAM type 1 (60-70%) (bronchial) (neonates and infants, resectable, good prognosis, possible carcinomatous change)
Synopsis
60-70%
bronchial type
neonates and infants
resectable
good prognosis
possible carcinomatous change (bronchioloalveolar carcinoma)
1 or more large cysts measuring 2-10 cm in diameter
larger cysts are often accompanied by smaller cysts
cyst walls containing muscle, elastic, or fibrous tissue
cysts frequently lined by pseudostratified columnar epithelial cells often interspersed with rows of mucous cells
focal mucous cell hyperplasia (12 to 25% of type 1 CCAM)
microscopic foci of bronchioloalveolar carcinoma (1 to 31% of type 1 CCAM) (#12883247#)
References
MacSweeney F, Papagiannopoulos K, Goldstraw P, Sheppard MN, Corrin B, Nicholson AG. An assessment of the expanded classification of congenital cystic adenomatoid malformations and their relationship to malignant transformation. Am J Surg Pathol. 2003 Aug;27(8):1139-46. PMID: #12883247#