cystic dysplasia of the rete testis
Cystic dysplasia of the rete testis (CDRT) is a rare congenital defect, characterized by multiple irregular cystic spaces in the mediastinum of the testis that may involve the whole gonad.
Synopsis
multiple, anastomosing, irregular cystic spaces of varying sizes and shapes separated by incomplete connective-tissue septa
- predominantly located in the mediastinum testis
- irregularly spread, displacing the testicular parenchyma, and consequently compressed under the tunica albuginea.
Ultrastructure
two types of epithelial cells lining the cystic spaces
- flattened cells
- tall cells
These cells were similar to those lining the normal adult rete testis
Physiopathology
Since the rete testis originates from the gonadal blastema, and the efferent ductules from the mesonephric ducts, an embryologic defect in the connection between both structures might be responsible for this lesion. (#6547323#)
Types
unilateral cystic dysplasia of the rete testis
bilateral cystic dysplasia of the rete testis
Association
ipsilateral wolffian duct anomalies
ipsilateral ureteral anomalies
- ipsilateral ectatic terminal ureter (#12602716#)
ipsilateral renal agenesis (#12602716#)
- and contralateral crossed ectopia (#12137846#, #12119430#)
- ipsilateral ectatic terminal ureter (#12602716#)
ipsilateral cystic renal dysplasia (#11910517#)
contralateral crossed renal ectopia (#12137846#)
renal adysplasia (#16822083#)
penoscrotal hypospadias (#11411661#)
unilateral cryptorchidism (undescended testicle) (#11411661#)
bilateral scrotal hernia (#11411661#)
small and hypocompliant bladder (#11411661#)
urethral obstruction (#11411661#)
See also
cystic testicular lesions
cystic transformation of the rete testis
References
Bouron-Dal Soglio D, Harvey I, Jovanovic M, Oligny LL, Fournet JC. Bilateral cystic dysplasia of the rete testis with renal adysplasia. Pediatr Dev Pathol. 2006 Mar-Apr;9(2):157-60. PMID: #16822083#
Camassei FD, Francalanci P, Ferro F, Capozza N, Boldrini R. Cystic dysplasia of the rete testis: report of two cases and review of the literature. Pediatr Dev Pathol. 2002 Mar-Apr;5(2):206-10. PMID: #11910517#
Loo CK, Yung T. Cystic dysplasia of the testis: a report of three cases and review of the literature. Pediatr Pathol Lab Med. 1995 Nov-Dec;15(6):885-93. PMID: #8705199#
Glantz L, Hansen K, Caldamone A, Medeiros LJ. Cystic dysplasia of the testis. Hum Pathol. 1993 Oct;24(10):1142-5. MID: #8406425#
Nistal M, Regadera J, Paniagua R. Cystic dysplasia of the testis. Light and electron microscopic study of three cases. Arch Pathol Lab Med. 1984 Jul;108(7):579-83. PMID: #6547323#