X-linked visceral heterotaxy

Synopsis

 cardiovascular anomalies

• dextrocardia
• corrected transposition of great arteries
• ventricular septal defect
• patent ductus arteriosus
• pulmonic stenosis

 situs inversus viscerum
 asplenia
 polysplenia

Etiology

 germline mutations in the ZIC3 gene (MIM.300265)

See also:

 autosomal visceral heterotaxy (MIM.605376)