PDKs
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The pyruvate dehydrogenase (PDH) complex is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals.
The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by specific pyruvate dehydrogenase kinases (PDKs) results in inactivation.
Components
| PDK1 | PDK2 | PDK3 |
See also
pyruvate
PDH