karyopherins
The karyopherin beta (or importin beta) family comprises soluble transport factors that mediate the movement of proteins and RNAs between the nucleus and cytoplasm.
Functions
mediate the movement of proteins and RNAs between the nucleus and cytoplasm
regulate assembly of the nuclear pore complex (NPC), assembly of the nuclear envelope, mitosis and replication.
recognize and transport many distinct cargoes and traverse the NPC
References
Mosammaparast N, Pemberton LF. Karyopherins: from nuclear-transport mediators to nuclear-function regulators. Trends Cell Biol. 2004 Oct;14(10):547-56. PMID: #15450977#