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DDXs

DEAD box proteins (DDXs) are putative RNA helicases that have a characteristic asp-glu-ala-asp (DEAD) box as 1 of 8 highly conserved sequence motifs.

By altering RNA secondary structure they can influence translation initiation, splicing, and ribosome and splicesome assembly.

Members

DDX1 DDX2 DDX3 DDX4 DDX5 DDX6 DDX7 DDX8 DDX9 DDX10
DDX11 DDX12 DDX13 DDX14 DDX15 DDX16 DDX17 DDX18 DDX19 DDX20
DDX21 DDX22 DDX23 DDX24 DDX25 DDX26 DDX27 DDX28 DDX29

Pathology

See also

- RNA helicases
- DNA helicases