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fulminant hepatitis

Clinicobiological syndrome associated with hepatic insufficiency and massive hepatocytic necrosis.

Etiology

- fulminant infectious hepatitis

  • fulminant viral hepatitis (54.2%)
  • fulminant virus A hepatitis

- fulminant drug-induced hepatitis (14.2%)

  • reversible valproate fulminant hepatic failure
  • tolcapone-related fulminant hepatitis
  • flutamide-associated acute liver failure

- fulminant dysimmune hepatitis

  • fulminant auto-immune hepatitis

- metabolic fulminant hepatitis

  • Wilson disease (11.4%)
  • Reye syndrome

- drug-induced fulminant hepatitis (drug-induced active liver failure)

Animal models

- Fas-mediated fulminant hepatitis in mice (TNFRSF6)

See also

- acute liver failure
- massive hepatic necrosis