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JAK3

MIM.600173 19p13.1

Pathology

- JAK3-associated SCID

  • germline mutations of JAK3 in T-, B+, NK- severe combined immunodeficiency (SCID) (MIM.600802)

See also

- JAKs
- JAK kinases signaling pathway

References

- Borie DC, O’shea JJ, Changelian PS. JAK3 inhibition, a viable new modality of immunosuppression for solid organ transplants. Trends Mol Med. 2004 Nov;10(11):532-41. PMID: #15519279#