renal spiradenocylindroma
CGH
i(16p) profile
- loss of 16q
- gain of 16p
Molecular biology
LOH at 16q12-13 with CYLD1 mutations
References
Strobel P, Zettl A, Ren Z, Starostik P, Riedmiller H, Storkel S, Muller-Hermelink HK, Marx A. Spiradenocylindroma of the kidney: clinical and genetic findings suggesting a role of somatic mutation of the CYLD1 gene in the oncogenesis of an unusual renal neoplasm. Am J Surg Pathol. 2002 Jan;26(1):119-24. PMID: #11756779#