GPI-anchor
Definition: A special form of glycosylation is the GPI anchor. This form of glycosylation functions to attach a protein to a hydrophobic lipid anchor, via a glycan chain.
Many cell surface proteins are anchored to the membrane by a glycolipid termed the glycosylphosphatidylinositol (GPI) anchor, which is covalently attached to the C-terminus of the peptide. The core of the GPI anchor consists of multiple components and its biosynthesis involves multiple genes, such as those for glycosyltransferases.
Members
| PIGA |
See also
prenylation