SNAP25
MIM.600322 20p11.2
The SNAP25 gene encodes a 25-kD protein of 206 amino acids.
SNAP25 is a presynaptic plasma membrane protein (SNAPs) that plays an important role in the synaptic vesicle membrane docking and fusion pathway. SNAP25 is a target SNARE (t-SNAREs).
SNAP25 has been demonstrated in conventional synaptic terminals in the retina that are absent from ribbon synapses, which play a key role in transferring information from photoreceptor cells to the central nervous system.
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 (MIM.600322) are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane.
See also:
SNAPs
SNAREs