profilins
Profilins are small actin-binding proteins.
In vitro, profilins regulate the dynamics of actin polymerization, which is their key role in vivo during cell motility.
Profilins function as hubs that control a complex network of molecular interactions in:
membrane trafficking
small-GTPase signaling
nuclear activities
Pathology
neurological diseases
tumor formation
References
Witke W. The role of profilin complexes in cell motility and other cellular processes. Trends Cell Biol. 2004 Aug;14(8):461-9. PMID: #15308213#