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MYH9

MIM.160775 22q11.2

Pathology

- germline mutations

  • germline mutation in the May-Hegglin anomaly (MIM.155100)
  • germline mutation in the Sebastian syndrome (MIM.605249)
  • germline mutation in the Fechtner syndrome (MIM.153640)
  • germline mutation in progressive hearing impairment with cochleosaccular degeneration (DFNA17) (MIM.603622)
  • germline mutation in Alport-like syndrome with macrothrombocytopenia (MIM.153650)

- MYH9/ALK fusion protein t(2;22)(p23;q11.2) in anaplastic large cell lymphoma (ALCL)