protein interaction domains
Proteins are controlled by a vast and dynamic array of post-translational modifications, many of which create binding sites for specific protein-interaction domains.
These domains, working together, could read the state of the proteome and therefore couple post-translational modifications to cellular organization.
Video
An example of interaction domains in protein-protein interaction (Il-1 and IL1R)
References
Seet BT, Dikic I, Zhou MM, Pawson T. Reading protein modifications with interaction domains. Nat Rev Mol Cell Biol. 2006 Jul;7(7):473-83. PMID: #16829979#