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TGF-beta signaling-associated diseases

Examples

- Loss-of-function mutations in Growth Differentiation Factor-1 (GDF1) are associated with congenital heart defects (#17924340#)

References

- Waite KA, Eng C. From developmental disorder to heritable cancer: it’s all in the BMP/TGF-beta family. Nat Rev Genet. 2003 Oct;4(10):763-73. PMID: #14526373#