Humpath.com - Human pathology - Photos - pictures - videos

signaling pathways

- MAPK signaling pathways (ras/MAPK pathways)

  • Ras/MEK/ERK signaling pathway (RAS-ERK signaling pathway)
  • JNK/MAPK signaling pathway

- Notch signaling pathway
- WNT signaling pathway (catenins/APC signaling pathway)
- PI3K/PTEN/AKT signaling pathway (phosphoinositol-3-kinase/Akt signaling pathway)
- TSC/FRAP1 pathway (TSC/mTOR pathway)
- NF-kappaB signaling pathway
- PKA signaling pathway
- SHH-GLI signaling pathway (Hedgehog-Patched signaling pathway)
- TGF-beta signaling pathway
- ErbB signaling pathway
- receptor tyrosine kinase signaling pathways
- JAKs/STATs signaling pathways
- nuclear hormone signaling pathways
- FANC/BRCA1/BRCA2/ATM/NBS1 signaling pathway (BRCAs signaling pathway)
- Rb/E2F signaling pathway (P16(INK4A)-CDK4/6-RB pathway)
- endothelin receptor signaling pathway
- ARF-MDM2-P53 signaling pathway
- caspases pathway
- insulin signaling pathway
- cytokine signaling pathways

  • IL-5 signaling pathway

Databases

- KEGG pathway database
- Biocarta

Softwares

- BioD, a visual language for describing, documenting and analyzing the functions of complex biological systems
- PathwayAssist, software tool for analysis, expansion and visualization of biological pathways
- GeneAssist Pathway Atlas

References

- Towards genome-scale signalling-network reconstructions. Hyduke DR, Palsson BO. Nat Rev Genet. 2010 Feb 23. PMID: #20177425#

- Bhalla US. Models of cell signaling pathways. Curr Opin Genet Dev. 2004 Aug;14(4):375-81. PMID: #15261653#

- Kabuyama Y, Resing KA, Ahn NG. Applying proteomics to signaling networks. Curr Opin Genet Dev. 2004 Oct;14(5):492-8. PMID: #15380239#

- Pires-daSilva A, Sommer RJ. The evolution of signalling pathways in animal development. Nat Rev Genet. 2003 Jan;4(1):39-49. PMID: #12509752#

- Tuveson DA, Fletcher JA. Signal transduction pathways in sarcoma as targets for therapeutic intervention. Curr Opin Oncol. 2001 Jul;13(4):249-55. PMID: #11429482#