MAPK signaling pathway
Image Gallery
[ (||image_reduire{0,60}|inserer_attribut{alt,Signal-transduction pathway of the TrkA tyrosine kinase receptor.}) ]
Members
| ERK | BRAF | RAS | MAPKs |
See also
RASs: HRAS, KRAS, NRAS
References
Kim IA, Fernandes AT, Gupta AK, McKenna WG, Bernhard EJ. The influence of Ras pathway signaling on tumor radiosensitivity. Cancer Metastasis Rev. 2004 Aug;23(3-4):227-36. PMID: #15197325#
Downward J. Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer. 2003 Jan;3(1):11-22. PMID: #12509763#
Stork PJ, Schmitt JM. Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation. Trends Cell Biol. 2002 Jun ;12(6):258-66. PMID : #12074885#
Hazzalin CA, Mahadevan LC. MAPK-regulated transcription: a continuously variable gene switch? Nat Rev Mol Cell Biol. 2002 Jan;3(1):30-40. PMID: #11823796#
Madhani HD, Fink GR. The riddle of MAP kinase signaling specificity. Trends Genet. 1998 Apr;14(4):151-5. PMID: #9594663#
Breitkreutz A, Tyers M. MAPK signaling specificity : it takes two to tango. Trends Cell Biol. 2002 Jun ;12(6):254-7. PMID : #12074884#