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CBFB

16q22

Rearrangements

- inv(16)(p13q22)
- t(16;16)(p13;q22)
- del(16)(q22)

Molecular biology

- CBFB/MYH11 fusion protein in acute myeloid leukemia, usually associated with bone marrow eosinophilia (M4Eo leukemia)

Tumors

- acute myeloid leukemia M4 (M4-ANLL)

  • associated with bone marrow eosinophilia (M4Eo-ANLL)