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endocervical glandular atypia
Tuesday 7 December 2021
endocervical glandular dysplasia ; endocervical glandular dysplasia (atypical hyperplasia) ; United Kingdom CGIN : cervical glandular intraepithelial neoplasia ; Glandular dysplasia
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Synopsis
Glandular atypia
- Glandular cells with hyperchromatic nuclei with only occasional mitotic figures and minimal pseudostratification
- No cribriform areas, no papillary projections, no crowding, no mitotic figures
- Alternatively there is marked atypia involving only a single gland
- Normal N/C ratio
Glandular dysplasia
- Resembles adenocarcinoma in situ but nuclei are not malignant and have fewer mitotic figures OR malignant involvement of only one gland
Differential diagnosis
reactive glandular atypia
Arias-Stella reaction
inflammation
microglandular hyperplasia
metaplasia
radiation
tamoxifen or oral contraceptives
See also
carvical anomalies