gallbladder epithelial dysplasia

Macroscopy

 Granular mucosal patches or no gross findings

Microscopy

 Involves flat mucosa, papillae, Rokitansky-Aschoff sinuses, metaplastic pyloric glands
 Abrupt transition from normal mucosa
 May resemble carcinoma but no desmoplasia
 Often goblet cells
 Low grade: crowding and hyperchromatic and elongated nuclei
 High grade: low grade features plus stratification; includes carcinoma in situ

See also

 anomalies of the gallbladder