Home > E. Pathology by systems > Reproductive system > Fetus and annexes > Placenta > vacuolization of syncytiotrophoblast
vacuolization of syncytiotrophoblast
Tuesday 22 August 2017
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Suspected skeletal dysplasia with pulmonary hypoplasia @ 37gw. Small placenta (304g) : GM1 gangliosidosis
- https://twitter.com/sranna86/status/899780925445165056
- Placental metabolic dysfunction due to GM1 gangliosidosis
- Placental shows vacuolisation of syncytiotrophoblast, intermediate trophoblast, and stromal Hofbauer cells.
- AR lysosomal storage disease characterised by def of acid beta-galactosidase resulting in accumulation of gangliosides and MPS in tissues.