uterine spindle cell tumors

Differential diagnosis

 endometrial stromal tumors (ESTs)

• endometrial stromal tumors may pose diagnostic challenges particularly when they exhibit variant histologic appearances, involve extrauterine sites, or present as metastatic disease. In such cases, use of immunohistochemical markers and identification of specific nonrandom chromosomal rearrangements may be helpful.
• endometrial stromal nodule (ESN): Stromal nodule does not have atypical mitoses, and has a lower number of mitosis.
• endometrial stroma sarcoma (ESS)

 uterine leiomyoma

• Classic leiomyoma is not this atypical or cellular (variants of leiomyoma include cellular leiomyoma and atypical leiomyoma).
• Leiomyoma is not CD10 positive.

 uterine leiomyosarcoma

• Leiomyosarcoma is not CD10 positive.

See also

 uterine tumors
 spindle cell tumors