KRAS/TP53-associated pancreatic adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a rapidly progressing disease associated with less than 10% 5-year survival rate.

See also

 KRAS
 TP53
 pancreatic adenocarcinoma
 PRMT1

Paywall references

 p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells. Bailey JM, Hendley AM, Lafaro KJ, Pruski MA, Jones NC, Alsina J, Younes M, Maitra A, McAllister F, Iacobuzio-Donahue CA, Leach SD. Oncogene. 2016 Aug 11;35(32):4282-8. doi : 10.1038/onc.2015.441
PMID: 26592447