KRT7
HGNC:6445 MIM.148059
Image Gallery
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CK7 expression in normal cells
biliary epithelial cells
CK7 expression in tumors
CK7 expression in tumors
- cutaneous Paget disease (#9500217#, #9331290#)
- Intraepidermal cytokeratin 7 expression is not restricted to Paget cells but is also seen in Toker cells and Merkel cells. (#9989849#)
mucinous cystadenocarcinoma of the breast
- All cases stain positively with cytokeratin 7 (CK7) but were negative with cytokeratin 20 (CK20).
papilary renal cell carcinoma
benign proliferative nipple duct lesions (#10555003#)
See also
KRT19 (CK19)
References
Breast cancer and mammary lesions
Benign proliferative nipple duct lesions frequently contain CAM 5.2 and anti-cytokeratin 7 immunoreactive cells in the overlying epidermis. Zeng Z, Melamed J, Symmans PJ, Cangiarella JF, Shapiro RL, Peralta H, Symmans WF. Am J Surg Pathol. 1999 Nov;23(11):1349-55. PMID: #10555003#
Mucinous cystadenocarcinoma of the breast. Koenig C, Tavassoli FA. Am J Surg Pathol. 1998 Jun;22(6):698-703. PMID: #9630176#
Paget disease
Intraepidermal cytokeratin 7 expression is not restricted to Paget cells but is also seen in Toker cells and Merkel cells. Lundquist K, Kohler S, Rouse RV. Am J Surg Pathol. 1999 Feb;23(2):212-9. PMID: #9989849#
Perianal Paget’s disease: a histologic and immunohistochemical study of 11 cases with and without associated rectal adenocarcinoma. Goldblum JR, Hart WR. Am J Surg Pathol. 1998 Feb;22(2):170-9. PMID: #9500217#
Vulvar Paget’s disease: a clinicopathologic and immunohistochemical study of 19 cases. Goldblum JR, Hart WR. Am J Surg Pathol. 1997 Oct;21(10):1178-87. PMID: #9331290#
Renal cell carcinomas
Renal cell carcinomas in children and young adults: increased incidence of papillary architecture and unique subtypes. Renshaw AA, Granter SR, Fletcher JA, Kozakewich HP, Corless CL, Perez-Atayde AR. Am J Surg Pathol. 1999 Jul;23(7):795-802. PMID: #10403302#