thyroid carcinomas
Image Gallery
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Synopsis
Mainly adults
Classification
well-differentiated carcinomas of the thyroid
- thyroid follicular carcinoma
- thyroid papillary carcinoma
- Hurthle cell thyroid carcinoma
anaplastic carcinoma of the thyroid
According to age
pediatric thyroid carcinomas
- rare but well-reported in childhood
- especially papillary carcinoma
- increased rate with radiation exposure
- tend to present with more advanced disease than adults with lymph node and lung metastases
- have higher recurrence rates but better overall survival
Molecular biology
expression profiling: #12738736#, #12707638#, #12480920#
cDNA libraries: #12480920#
CTNNB1 exon 3 mutations in poorly differentiated (25%) and undifferentiated thyroid carcinomas (21.4%) (#11238046#)
Predisposition
familial thyroid cancers
References
Alsanea O, Clark OH. Familial thyroid cancer. Curr Opin Oncol. 2001 Jan;13(1):44-51. PMID: #11148685#