papillary hidradenoma

Definition: Hidradenoma papilliferum is a benign apocrine lesion found almost exclusively in women, most often the labia majora.

Hidradenoma papilliferum (papillary hidradenoma) is almost exclusively observed in women, in vulva or perianal area.

Microscopy

It forms a well-circumscribed dermal nodule with papillary projections with a fibrous stroma. They are lined with a double-layered epithelium composed of inner cuboidal myoepithelial cells and outer columnar cells with eosinophilic cytoplasm.

The outer cells may demonstrate decapitation secretion, in which the apical portion of the outer cells pinch off; this feature is frequently observed in apocrine lesions.

Images

 vulvar hidradenoma papilliferum

• https://twitter.com/DCSkipperDO/status/726546121099755520
• https://twitter.com/luishcruzc/status/847232028558807042
• https://twitter.com/noymiguel_md/status/1187173486743183360

 perianal hidradenoma papilliferum

• https://twitter.com/ARP_Press/status/776170590877126656

Localization

 vulvar hidradenoma papilliferum
 perianal hidradenoma papilliferum

See also

 cutaneous tumors

• cutaneous adnexal tumors