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single-cell mutational profiling
Tuesday 7 January 2014
References
Single-cell mutational profiling and clonal phylogeny in cancer. Potter NE, Ermini L, Papaemmanuil E, Cazzaniga G, Vijayaraghavan G, Titley I, Ford A, Campbell P, Kearney L, Greaves M. Genome Res. 2013 Dec;23(12):2115-25. doi : 10.1101/gr.159913.113 PMID: 24056532
Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing. Heitzer E, Auer M, Gasch C, Pichler M, Ulz P, Hoffmann EM, Lax S, Waldispuehl-Geigl J, Mauermann O, Lackner C, Höfler G, Eisner F, Sill H, Samonigg H, Pantel K, Riethdorf S, Bauernhofer T, Geigl JB, Speicher MR. Cancer Res. 2013 May 15;73(10):2965-75. doi : 10.1158/0008-5472.CAN-12-4140 PMID: 23471846
Sequencing cells one at a time offers singular insight into cancer. Erdmann J. Nat Med. 2012 Jun 6;18(6):842. doi : 10.1038/nm0612-842a PMID: 22673984