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hepatic CGD

Digital slides

- Case 20 : Foamy macrophages in portal spaces - Chronic granulomatous disease

Synopsis

- pigmented-lipid histiocytosis (pigmented histiocytes)

  • lipofuscin pigment in histiocytes
  • clusters of hypertrophied and pigmented portal macrophages
  • clusters of hypertrophied and pigmented Kupffer cells
  • clusters of hypertrophied light tan coloured portal macropahges
    - palissading granulomas with central necrosis or central suppuration
  • necrotizing granulomas
    - hepatic abscesses
    - lobular microabscesses
    - hepar lobatum-like cirrhosis

See also

- chronic granulomatous disease (CGD)