CDC7L1
MIM.603311 1p21
Cell division cycle 7 is a widely expressed protein kinase implicated in cell division, cell cycle checkpoint mechanisms, and cancer progression.
Pathology
CDC7 gene is overexpressed in some tumors and transformed cell lines. (#9573348#)
breast carcinomas
- Cell division cycle 7 is a replication associated protein with relationships to gene amplification and genomic instability in breast carcinomas. (#19896697#)
References
Overexpression of cell division cycle 7 homolog is associated with gene amplification frequency in breast cancer. Choschzick M, Lebeau A, Marx AH, Tharun L, Terracciano L, Heilenkötter U, Jaenicke F, Bokemeyer C, Simon R, Sauter G, Schwarz J. Hum Pathol. 2009 Nov 5. PMID: #19896697#
Hess, G. F.; Drong, R. F.; Weiland, K. L.; Slightom, J. L.; Sclafani, R. A.; Hollingsworth, R. E. : A human homolog of the yeast CDC7 gene is overexpressed in some tumors and transformed cell lines. Gene 211: 133-140, 1998. PubMed ID : #9573348#