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chondroblastic osteosarcoma

Digital cases

- Case 115 : Chondroblastic osteosarcoma of the calcaneum

Definition : Chondroblastic osteosarcoma (OS) accounts for about 25% of all cases of OS.

Localization

- flat bones

  • temporal bone (#20730902#)

Differential diagnosis

It can pose diagnostic difficulty on cytology, as the tumor cells may resemble the carcinomatous cells.

Prognosis

A chondroblastic subtype of osteosarcoma could be at risk to have a higher risk for late relapse. (#16426841#)

See also

- osteosarcomas

References

- Galectin-1 is a powerful marker to distinguish chondroblastic osteosarcoma and conventional chondrosarcoma. Gomez-Brouchet A, Mourcin F, Gourraud PA, Bouvier C, De Pinieux G, Le Guelec S, Brousset P, Delisle MB, Schiff C. Hum Pathol. 2010 Sep;41(9):1220-30. PMID: #20399482#

- Clinico-histologic parameters of osteosarcoma patients with late relapse. Hauben EI, Bielack S, Grimer R, Jundt G, Reichardt P, Sydes M, Taminiau AH, Hogendoorn PC. Eur J Cancer. 2006 Mar;42(4):460-6. PMID: #16426841#