omental GIST
Gastrointestinal stromal tumors (GISTs), generally KIT-positive and KIT/PDGFRA mutation-driven mesenchymal neoplasms, most commonly originate from the stomach or small intestine, but in rare examples they involve the omentum.
Omental GISTs unattached to gastrointestinal tract often resemble gastric GISTs suggesting that they may be gastric GISTs directly extending or parasitically attached into the omentum, whereas multiple omental GISTs more often resemble small intestinal GISTs suggesting that they may be metastatic or detached from this source. (#19440146#)
KIT positive Cajal cells are not found in normal omental tissues failing to support the presence of these ancestral cells for GIST in the omentum. (#19440146#)
References
Gastrointestinal Stromal Tumors Presenting as Omental Masses-A Clinicopathologic Analysis of 95 Cases. Miettinen M, Sobin LH, Lasota J. Am J Surg Pathol. 2009 May 13. PMID: #19440146#