calcifying fibrous tumor
Definition: Calcifying fibrous tumor (CFT) is a rare benign mesenchymal tumor composed of hyalinized fibrous tissue with interspersed bland fibroblastic spindled cells, scattered psammomatous, and/or dystrophic calcifications and variably prominent mononuclear inflammatory infiltrate. CFTs show a predilection for the abdominal cavity and soft tissue.
Calcifying fibrous tumor, formerly known as calcifying fibrous pseudotumor, is now recognized to occur at a wide variety of anatomical sites, mainly in children and young adults.
It which may recur locally and consists of hypocellular/hyalinized fibrous tissue containing scattered lymphocytes, plasma cells and stromal calcifications which are often psammomatous in appearance.
References
Calcifying fibrous tumor of the stomach: clinicopathologic and molecular study of seven cases with literature review and reappraisal of histogenesis. Agaimy A, Bihl MP, Tornillo L, Wünsch PH, Hartmann A, Michal M. Am J Surg Pathol. 2010 Feb;34(2):271-8. PMID: #20090503#
The evolving classification of soft tissue tumours: an update based on the new WHO classification. Fletcher CD. Histopathology. 2006 Jan;48(1):3-12. PMID: #16359532#