premature aging diseases

Classification

 Werner syndrome (MIM.277700)
 Bloom syndrome (MIM.210900)
 RECQL4 (MIM.603781) : mutations in the Rothmund-Thomson syndrome (MIM.268400)
 RECQL5 (MIM.603781)
 Progeria (mutations in lamin A/C)

References

 Razzaque MS, Lanske B. Hypervitaminosis D and premature aging: lessons learned from Fgf23 and Klotho mutant mice. Trends Mol Med. 2006 Jul;12(7):298-305. PMID: 16731043

 Chang S. Modeling premature aging syndromes with the telomerase knockout mouse. Curr Mol Med. 2005 Mar;5(2):153-8. PMID: 15974868

 Novelli G, D’Apice MR. The strange case of the "lumper" lamin A/C gene and human premature ageing. Trends Mol Med. 2003 Sep;9(9):370-5. PMID: 13129702

 Bohr VA: Human premature aging syndromes and genomic instability. Mech Ageing Dev 123:987, 2002.