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IFNGR1

MIM.107470 6q23-q24

The human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2 (147569). IFNGR1 is the ligand-binding subunit.

Pathology

- germline mutations in

  • familial disseminated atypical mycobacterial infection (MIM.209950)
  • fatal BCG infection (MIM.209950)

- variants in

  • susceptibility to Helicobacter pylori infection

See also

- interferons