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GABRA1

MIM.137160 5q34-q35

The GABA-A receptor is the receptor for the major inhibitory neurotransmitter in the vertebrate brain.

Pathology

- germline mutations in

  • juvenile myoclonic epilepsy (JME) (MIM.606904)
  • childhood absence epilepsy locus 4 (ECA4) (MIM.611136)