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type 3 RTKs

The gene for KDR (kinase insert domain receptor) code for a growth factor receptor tyrosine kinase.

Type III receptor tyrosine kinases contained multiple characteristics: an ATP binding site, a membrane spanning region, split tyrosine kinase regions.

Exemples

- platelet-derived growth factor receptor-B (PDGFRB MIM.173410)
- colony stimulating factor-1 receptor (CSF1R MIM.164770)
- fibroblast growth factor receptor-2 (FGFR2 MIM.176943)
- KIT (MIM.164920))
- KDR

See also

- membrane repceptors