Home > E. Pathology by systems > Skin > alopecia areata
alopecia areata
Monday 3 December 2007
Definition: Alopecia areata (AA) is a genetically determined, immune-mediated disorder of the hair follicle that affects 1%-2% of the U.S. population. It is defined by a spectrum of severity that ranges from patchy localized hair loss on the scalp to the complete absence of hair everywhere on the body.
Images
33yo F parietal scalp
Loci
chromosome 18
chromosome 16
chromosome 6q
chromosome 6p
See also
alopecia
hair loss
hair follicle loss
hair follicle anomalies
References
Martinez-Mir A, Zlotogorski A, Gordon D, Petukhova L, Mo J, Gilliam TC, Londono D, Haynes C, Ott J, Hordinsky M, Nanova K, Norris D, Price V, Duvic M, Christiano AM. Genomewide scan for linkage reveals evidence of several susceptibility loci for alopecia areata. Am J Hum Genet. 2007 Feb;80(2):316-28. PMID: 17236136
