DLX6

Many vertebrate genes have been identified by virtue of their nucleotide sequence similarity with Drosophila developmental genes. Many homeobox-containing genes have been identified on this basis.

The Dlx gene family (DLXs) has been identified because these genes contain a homeobox related to that of Distal-less (Dll, also known as Ba), a gene expressed in the head and limbs of the developing fruit fly.

References

 Schule B, Li HH, Fisch-Kohl C, Purmann C, Francke U. DLX5 and DLX6 expression is biallelic and not modulated by MeCP2 deficiency. Am J Hum Genet. 2007 Sep;81(3):492-506. PMID: 17701895