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prostatic yolk sac tumor

Variants

- combined focal seminoma of the prostate

Synopsis

- papillary and glandular epithelium
- fibrous or myxoid stroma
- Schiller-Duval bodies
- periodic acid-Schiff-positive hyaline bodies

Immunochemistry

- alpha-fetoprotein +
- cytokeratin +/-
- placental alkaline phosphatase -
- prostate-specific antigen -
- prostatic acid phosphatase -
- carcinoembryonic antigen
- vimentin -
- chromogranin A -
- human chorionic gonadotropin - (HCG -)

See also

- primary endodermal sinus tumor (EST) (yolk sac tumor)

References

- Han G, Miura K, Takayama T, Tsutsui Y. Primary prostatic endodermal sinus tumor (yolk sac tumor) combined with a small focal seminoma. Am J Surg Pathol. 2003 Apr;27(4):554-9. PMID: #12657943#