penile myointimoma
Penile myointimoma is a rare benign myointimal proliferation occurring exclusively within the corpus spongiosum of the glans penis and is most commonly described in adult patients.
Synopsis
myointimal proliferation of the preexisting vascular spaces of the corpus spongiosum, creating a multinodular/plexiform architecture.
Immunohistochemistry
strong cytoplasmic immunoreactivity for smooth muscle actin in the lesional cells
collarette of native smooth muscle highlighted by desmin
References
McKenney JK, Collins MH, Carretero AP, Boyd TK, Redman JF, Parham DM. Penile Myointimoma in Children and Adolescents: A Clinicopathologic Study of 5 Cases Supporting a Distinct Entity. Am J Surg Pathol. 2007 Oct;31(10):1622-1626. PMID: #17895766#