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peromelia

Definition: Severe congenital malformations of limbs, including absence of hand or foot.

Etiology

- chromosomal anomalies

  • de novo balanced reciprocal t(2; 12)(p25.1;q24.1) (#12002154#)

References

- Murray RS, Keeling JW, Ellis PM, FitzPatrick DR. Symmetrical upper limb peromelia and lower limb phocomelia associated with a de novo apparently balanced reciprocal translocation: 46,XX,t(2;12)(p25.1;q24.1). Clin Dysmorphol. 2002 Apr;11(2):87-90. PMID: #12002154#