AKT2
AKT2 (MIM.164731) is the isoform of AKT 1 and is enriched in insulin-responsive tissues and has been implicated in the metabolic actions of the hormone.
Pathology
mutations and/or amplification in tumors
- ovarian carcinomas (#16839745#, #16721043#)
- pancreatic carcinomas (#14735903#)
- mammary carcinomas (#12032855#)
- embryonal rhabdomyosarcoma (#16790082#)
See also
AKTs