splenic anomalies

See also : splenic diseases

Types

• splenic macroscopical anomalies
• splenic microscopical anomalies

Macroscopical anomalies

Microscopical anomalies

 anomalies of white pulp

• white pulp depletion
• splenic reactive follicular hyperplasia

 anomalies of red pulp

• red pulp hemosiderin deposition
• red pulp cellular infiltration
  • sinusal cellular infiltration
  • cord cellular infiltration
    • cord plasmocytic infiltration
    • cord lymphoplasmocytic infiltration
    • cord myeloblastic infiltration
    • cord myelomonocytic infiltration
• splenic congestion in cords and sinuses (congestion of red pulp)
• red pulp extramedullary hematopoiesis
• red pulp erythrophagocytosis with neutrophils
• red pulp erythrophagocytosis with neutrophils
• empty appearance of sinuses (actually contain ghost red blood cells)
• prominent endothelial sinus lining
• red pulp hemosiderin deposition
• red pulp erythrophagocytosis
• expansion of red pulp
• immunoblastic proliferation in red pulp
• red pulp immunoblasts with atypical morphology, resembling Reed-Sternberg cells
• immunoblastic infiltration of subintima of intratrabecular veins

 global anomalies

• splenic spindle cell proliferation
• splenic perivascular hyalinization
• splenic hemosiderin deposition
• splenic inferct / splenic infarction
• splenic fibrosis

 splenic deposition of pink amorphous material

• deposition of pink amorphous material limited either to germinal follicles (sago spleen)
• deposition of pink amorphous material along splenic sinusoids
• deposition of pink amorphous material in surrounding connective tissue (lardaceous spleen)

 splenic deposition of amyloid (amyloidosis)

• deposition of amyloid limited either to germinal follicles (sago spleen)
• deposition of amyloid along splenic sinusoids
• deposition of amyloid in surrounding connective tissue (lardaceous spleen)

See also

 splenic malformations
 splenic lesions

• splenic macroscopical lesions
• splenic microscopical lesions

Links

 http://www.esp-pathology.org/pdf/hematopathology.pdf